access to our work

An overview of the progress towards the objectives of SimCardioTest, including milestones and deliverables are available here.

WP1 – Model Standardisation & Interoperability
WP2 – Use Case 1 – Pacing Leads & Catheters
WP3 – Use Case 2 – Left Atrial Appendage Occluder
WP4 – Drugs, Efficacy & Cardiotoxicity
WP5 – In-silico Trials & Data Science
WP6 – Verification, Validation, Uncertainty Quantification & Certification
WP7 – Exploitation, Dissemination & Communication
WP8 – Project Coordination & Management
WP9 – Ethics

Deliverables

  • D2.1 Report on the standardised models for interventional devices (Use Case 1)
    December 2021 - UC1 computational pipelines and input-output standardized formats
    D2.1 Report on standardised model for leads and catheters
  • D2.2. Demonstration of several catheters simulated and real ones
    June 2022 - Examples of navigation of a lead numerical model inside a virtual anatomy, and the same scenario in a benchmark where the real commercial lead is navigated through a 3D printed anatomical phantom.
    D2.2. Demonstration of several catheters simulated and real ones
  • D2.4 - Evaluation of fatigue models against experimental data
    March 2023 - Report on the 3D model and physical phantom that were developed to study the implantation of a cardiac pacing lead.
    Confidential
  • D3.1 Report on the standardised models for LAAO devices (Use Case 2)
    December 2021 - Workflow and input-output standardised formats for LAAO device modelling (Use Case 2)
    D3.1 Report on standardised model for LAAO devices
  • D3.2 Fluid simulations with optimised boundary conditions.
    June 2022 - Sensitivity analyses of relevant parameters for realistic fluid simulations.
    D3.2_Fluid simulations with optimised boundary conditions
  • D3.3 - Demonstration of interactive tool for LAAO device setting selection
    December 2022 - Video recording of Use Case 2 cloud-based platform demo

    Confidential
  • D3.4 - Database of fluid simulations in virtual population
    December 2022 - Database structure and workflow for virtual population development
    D3.4 Database of fluid simulations in virtual population
  • D3.5 -  LAAO device implantation simulations in virtual population
    December 2022
    Confidential
  • D5.1 Report on the in-silico trial of pacing leads & catheters
    December 2023 - In silico trial that determines the proportion of population that undergoes loss-of-capture due to fibrosis after implantation of a bradycardia pacemaker in the right ventricle
    D5.1_UC1_Report on In Silico Trial of pacing leads & catheters
  • D5.2 Report on the in-silico trial of the virtual population's fluid simulation database.
    December 2023
    Confidential
  • D5.3  Report on the in-silico trial of drug efficacy & cardiotoxicity
    December 2023 - In-silico trial tool to determine drug concentrations assuring TdP-related safety in different groups of patients. Example with Dofetilide
    D5.3_UC3_Report on the in-silico trial of drug efficacy & cardiotoxicity
  • D6.1 Verification & uncertainty quantification for the 3 use cases
    June 2023 - Implementation of Verification on a selection of Models developed for the Use Cases of WP2-4
    Upcoming
  • D6.2 Validation of the model predictions for the use cases
    June 2023 - Implementation of Validation on a selection of Models developed for the Use Cases of WP2-4
    Upcoming
  • D7.1 Dissemination and Communication strategy plan
    February 2021 - Report on the communication and dissemination activities strategy for the project.
    D7.1 Communication-Dissemination Strategy plan Revised
  • D7.2 Website and online presence
    May 2021 - Report on activities conducted for Project website and social media accounts online.
    D7.2website
  • D7.3 - Preliminary Exploitation strategy and market assessment
    December 2022 - Preliminary description of exploitable outputs and their exploitation strategy
    Confidential
  • D7.4 - Communication toolkits for physicians & patient organisations
    February 2024
    D7.4_Communication_toolkits_for_physicians_and_patient_organisations
  • D8.1 SimCardiotest WP8 Online space
    January 2021 - Report on the necessary tools for project management
    Confidential
  • D8.2  Project Quality Plan
    March 2021 - Document to guide the team and the stakeholders on the quality requirements, standards and the quality assurance mechanisms of the project.
    Confidential
  • D8.3 Intellectual Property management plan
    June 2021 - Report to detail the IP management
    D8.3 intellectual property Management plan
  • D8.4 -AB recommendation & SG request
    June 2022 - Report on the first feedback from the Advisory Board and request from the stakeholder group
    Confidential
  • D8.5 - Intermediate Advisory Board recommendations and stakeholder group’s request
    June 2023
    D8.5_intermediate report AB recommendations & SG request

  • D8.7 Data management plan
    June 2021 - Report to detail the data management
    D8.7 Data_Management
  • D9.1 POPD - Requirement No. 2
    June 2021 - Document on responses to EC ethics requirements
    Confidential

Milestones

  • D7.1 Dissemination and Communication strategy plan
    February 2021 - Report on the communication and dissemination activities strategy for the project.
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